Filamen. OverviewExternal linksFilamins are a class of proteins that hold two actin filaments at large angles Filamin protein in mammals is made up of an actinbinding domain at its Nterminus that is followed by 24 immunoglobulinlike repeat modules of roughly 95 amino acids There are two hinge regions between repeats 1516 and 2324 Filamin gets cleaved at these hinge regions to generate smaller fragments of the protein Filamin has two actinbinding sites with a Vlinkage between them so t Text under.
The meaning of FILAMENT is a single thread or a thin flexible threadlike object process or appendage How to use filament in a sentence.
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Altered filamin A enables amyloid beta induced tau hyperphosphorylation and neuroinflammation in Alzheimer’s disease Neuroimmunol Neuroinflammation 2017426371 Zhang L Huang T Teaw S Nguyen LH Hsieh LS Gong X Burns LH Bordey A Filamin A inhibition reduces seizure activity in a mouse model of focal cortical malformations.
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