Amlodipine 10 Mg Valsartan 160 Mg Tablet. Toedieningsvorm Tablet omhuld Bevat per tablet amlodipine (als besilaat) 5 mg valsartan 160 mg.
Julius S Kjeldsen SE Weber M et al Outcomes in hypertensive patients at high cardiovascular risk treated with regimens based on valsartan or amlodipine the VALUE randomised trial Lancet.
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Two hours after initiating a dose increase (160 to 320 mg/day) of valsartan a patient developed angioedema (ie swelling of lips and tongue) Symptoms resolved following a reduction in dose to the original dosage of 160 mg/day Very rare (less than 001%) Angioedema Cardiovascular Common (1% to 10%) Symptomatic hypotension in 55% of.
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Absorption An oral dose of hydrochlorothiazide is 6575% bioavailable with a T max of 15 hours and a C max of 70490ng/mL following doses of 125100mg 1011 When taken with a meal bioavailability is 10% lower C max is 20% lower and T max increases from 16 to 29 hours 11 Volume of distribution The volume of distribution varies widely from one study to another with.
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Initial dose 13 mg/kg once a day (up to 40 mg) Maintenance dose up to 27 mg/kg (up to 160 mg) once a day titrated according to patient response Comments I f the calculated dosage does not correspond to the available tablet strengths or if children are unable to swallow tablets the use of a suspension (which can be prepared from the tablets) is recommended.